Use of a volume-and pressure-limited mechanical ventilation strategy improves clinical
outcomes of patients with acute lung injury and acute respiratory distress syndrome …

A cornerstone of modern biomedical research is the use of mouse models to explore basic
pathophysiological mechanisms, evaluate new therapeutic approaches, and make go or no …

Human survival from injury requires an appropriate inflammatory and immune response. We
describe the circulating leukocyte transcriptome after severe trauma and burn injury, as well …

Background Treatment with a gonadotropin-releasing hormone agonist decreases bone
mineral density and increases the risk of fracture in men with prostate cancer. We conducted …

Background It is unclear whether an evaluation incorporating coronary computed
tomographic angiography (CCTA) is more effective than standard evaluation in the …

Importance Data on the efficacy of hydroxychloroquine for the treatment of coronavirus
disease 2019 (COVID-19) are needed. Objective To determine whether hydroxychloroquine …

Background The diagnostic criteria for acute lung injury (ALI) and ARDS utilize the Pa o
2/fraction of inspired oxygen (F io 2)[P/F] ratio measured by arterial blood gas analysis to …

BACKGROUND: The benefits of early continuous neuromuscular blockade in patients with
acute respiratory distress syndrome (ARDS) who are receiving mechanical ventilation …

In patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), a
recent ARDS Network randomized controlled trial demonstrated that a low tidal volume (Vt) …

Blacks have significantly higher rates of hypertension than whites, and lower circulating
levels of 25-hydroxyvitamin D. There are few data about the effect of vitamin D3 …