[PDF][PDF] Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7
We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70
in multiple independent lineages, often occurring after acquisition of receptor binding motif …
in multiple independent lineages, often occurring after acquisition of receptor binding motif …
[HTML][HTML] Metagenomic next-generation sequencing aids the diagnosis of viral infections in febrile returning travellers
H Jerome, C Taylor, VB Sreenu, T Klymenko… - Journal of Infection, 2019 - Elsevier
Objectives Travel-associated infections are challenging to diagnose because of the broad
spectrum of potential aetiologies. As a proof-of-principle study, we used MNGS to identify …
spectrum of potential aetiologies. As a proof-of-principle study, we used MNGS to identify …
SARS-CoV-2 lineage B. 1.1. 7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study
O Stirrup, F Boshier, C Venturini… - BMJ open …, 2021 - bmjopenrespres.bmj.com
Background SARS-CoV-2 lineage B. 1.1. 7 has been associated with an increased rate of
transmission and disease severity among subjects testing positive in the community. Its …
transmission and disease severity among subjects testing positive in the community. Its …
[HTML][HTML] Reduction of natural killer but not effector CD8 t lymphoyctes in three consecutive cases of severe/lethal H1N1/09 influenza a virus infection
Background The cause of severe disease in some patients infected with pandemic influenza
A virus is unclear. Methodology/Principal Findings We present the cellular immunology …
A virus is unclear. Methodology/Principal Findings We present the cellular immunology …
Insight into PCR testing for surgeons
A Mahanama, E Wilson-Davies - Surgery (Oxford), 2021 - Elsevier
The most commonly used molecular diagnostic technique is the polymerase chain reaction
(PCR). PCR detects a short section of genetic code of interest, a cancer gene, human mRNA …
(PCR). PCR detects a short section of genetic code of interest, a cancer gene, human mRNA …
[HTML][HTML] Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes
S Cotton, MP McHugh, R Dewar, JG Haas… - Journal of Hospital …, 2023 - Elsevier
Background The first epidemic wave of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In …
(SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In …
[HTML][HTML] The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study
FAT Boshier, C Venturini, O Stirrup… - Journal of Infection, 2021 - Elsevier
Abstract Objectives: Recently emerging SARS-CoV-2 variants have been associated with an
increased rate of transmission within the community. We sought to determine whether this …
increased rate of transmission within the community. We sought to determine whether this …
Concerning the OptiGene Direct LAMP assay, and it's use in at-risk groups and hospital staff
ESW Wilson-Davies, AIK Mahanama… - Journal of …, 2021 - journalofinfection.com
The COVID-19 pandemic has triggered an unprecedented demand for diagnostic tests.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is highly contagious in the …
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is highly contagious in the …
Investigations, actions and learning from an outbreak of SARS-CoV-2 infection among healthcare workers in the United Kingdom
K Saeed, E Pelosi, N Mahobia… - Journal of Infection …, 2021 - journals.sagepub.com
Background: We report an outbreak of SARS coronavirus-2 (SARS-CoV-2) infection among
healthcare workers (HCW) in an NHS elective healthcare facility. Methodology: A narrative …
healthcare workers (HCW) in an NHS elective healthcare facility. Methodology: A narrative …
Liver function tests in primary care provide a key opportunity to diagnose and engage patients with hepatitis C
A McLeod, SJ Hutchinson, A Weir, S Barclay… - Epidemiology & …, 2022 - cambridge.org
Since the advent of direct-acting antiviral therapy, the elimination of hepatitis c virus (HCV)
as a public health concern is now possible. However, identification of those who remain …
as a public health concern is now possible. However, identification of those who remain …