Summary α1-antitrypsin deficiency is a genetic disorder that affects about one in 2000–5000
individuals. It is clinically characterised by liver disease and early-onset emphysema …

Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity, mortality, and resource use worldwide. The goal of this Official American Thoracic …

α1-Antitrypsin (AAT) deficiency is an underrecognized genetic condition that affects
approximately 1 in 2,000 to 1 in 5,000 individuals and predisposes to liver disease and early …

Rationale: Electronic noses are successfully used in commercial applications, including
detection and analysis of volatile organic compounds in the food industry. Objectives: We …

Objective: To review current knowledge about the hepatopulmonary syndrome, including
definition and clinical features, methods for diagnosing it, pathophysiologic mechanisms of …

For all its traditional successes, the current model of medical education in the United States
and Canada is being challenged on issues of quality, throughput, and cost, a process that …

Background: Improving a patient's ability to self-monitor and manage changes in chronic
obstructive pulmonary disease (COPD) symptoms may improve outcomes. Objective: To …

Since the first American Thoracic Society statement regarding the diagnosis and
management of severe alpha-1 antitrypsin (AAT) deficiency in 1989 (1) and the initial …

Health-care professionals (HCPs) can provide protocol-based care that has a measurable
impact on critically ill patients beyond their liberation from mechanical ventilation (MV) …

Long-term use of supplemental oxygen improves survival in patients with COPD and severe
resting hypoxemia. However, the role of oxygen in symptomatic patients with COPD and …