Mechanisms of vascular damage in obstructive sleep apnea

M Kohler, JR Stradling - Nature Reviews Cardiology, 2010 - nature.com
Obstructive sleep apnea (OSA) is characterized by repetitive apnea–hypopnea cycles
during sleep, which are associated with oxygen desaturation and sleep disruption. Up to …

A systematic review of continuous positive airway pressure for obstructive sleep apnoea–hypopnoea syndrome

C McDaid, KH Durée, SC Griffin, HLA Weatherly… - Sleep medicine …, 2009 - Elsevier
We conducted a systematic review of current evidence on the effectiveness of continuous
positive airway pressure (CPAP) for treatment of obstructive sleep apnoea–hypopnoea …

The epidemiology of sleep apnoea.

RJ Davies, JR Stradling - Thorax, 1996 - ncbi.nlm.nih.gov
We conducted a study of the prevalence of sleep-disordered breathing in subjects derived
from a random sample of thepopulation. A total of 2,202 subjects 35 to 69yr of age were …

Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial

JCT Pepperell, S Ramdassingh-Dow, N Crosthwaite… - The Lancet, 2002 - thelancet.com
Background Obstructive sleep apnoea is associated with raised blood pressure. If blood
pressure can be reduced by nasal continuous positive airway pressure (nCPAP), such …

Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial

C Jenkinson, RJO Davies, R Mullins, JR Stradling - The Lancet, 1999 - thelancet.com
Background Nasal continuous positive airway pressure (NCPAP) is widely used as a
treatment for obstructive sleep apnoea. However, to date there are no randomised controlled …

Effect of home noninvasive ventilation with oxygen therapy vs oxygen therapy alone on hospital readmission or death after an acute COPD exacerbation: a …

PB Murphy, S Rehal, G Arbane, S Bourke… - Jama, 2017 - jamanetwork.com
Importance Outcomes after exacerbations of chronic obstructive pulmonary disease (COPD)
requiring acute noninvasive ventilation (NIV) are poor and there are few treatments to …

Effect of CPAP on insulin resistance and HbA1c in men with obstructive sleep apnoea and type 2 diabetes

SD West, DJ Nicoll, TM Wallace, DR Matthews… - Thorax, 2007 - thorax.bmj.com
Background: The effects of continuous positive airway pressure (CPAP) for obstructive sleep
apnoea (OSA) on insulin resistance are not clear. Trials have found conflicting results and …

Prevalence of obstructive sleep apnoea in men with type 2 diabetes

SD West, DJ Nicoll, JR Stradling - Thorax, 2006 - thorax.bmj.com
Background: A study was undertaken to establish the prevalence of obstructive sleep
apnoea (OSA) in men with type 2 diabetes. Methods: Men with type 2 diabetes from local …

A randomized controlled trial of adaptive ventilation for Cheyne–Stokes breathing in heart failure

JCT Pepperell, NA Maskell, DR Jones… - American journal of …, 2003 - atsjournals.org
Heart failure is associated with Cheyne–Stokes breathing, which fragments patients' sleep.
Correction of respiratory disturbance may reduce sleep fragmentation and excessive …

Case-control study of 24 hour ambulatory blood pressure in patients with obstructive sleep apnoea and normal matched control subjects

CWH Davies, JH Crosby, RL Mullins, C Barbour… - Thorax, 2000 - thorax.bmj.com
BACKGROUND There is considerable debate regarding the relationship between
obstructive sleep apnoea (OSA) and hypertension. It is unclear whether OSA is an …