[HTML][HTML] Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical …

JA Silversides, E Major, AJ Ferguson, EE Mann… - Intensive care …, 2017 - Springer
Background It is unknown whether a conservative approach to fluid administration or
deresuscitation (active removal of fluid using diuretics or renal replacement therapy) is …

Guidelines on the management of acute respiratory distress syndrome

MJD Griffiths, DF McAuley… - BMJ open …, 2019 - bmjopenrespres.bmj.com
The Faculty of Intensive Care Medicine and Intensive Care Society Guideline Development
Group have used GRADE methodology to make the following recommendations for the …

Staphylococcal toxic shock syndrome: mechanisms and management

JA Silversides, E Lappin, AJ Ferguson - Current infectious disease reports, 2010 - Springer
Staphylococcal toxic shock syndrome is a rare complication of Staphylococcus aureus
infection in which bacterial toxins act as superantigens, activating very large numbers of T …

[HTML][HTML] Clinical review: Acute respiratory distress syndrome-clinical ventilator management and adjunct therapy

JA Silversides, ND Ferguson - Critical Care, 2013 - Springer
Acute respiratory distress syndrome (ARDS) is a potentially devastating form of acute
inflammatory lung injury with a high short-term mortality rate and significant long-term …

Deresuscitation of patients with iatrogenic fluid overload is associated with reduced mortality in critical illness

JA Silversides, E Fitzgerald… - Critical Care …, 2018 - journals.lww.com
Objectives: To characterize current practice in fluid administration and deresuscitation
(removal of fluid using diuretics or renal replacement therapy), the relationship between fluid …

[HTML][HTML] Fluid balance, intradialytic hypotension, and outcomes in critically ill patients undergoing renal replacement therapy: a cohort study

JA Silversides, R Pinto, R Kuint, R Wald… - Critical care, 2014 - Springer
Introduction In this cohort study, we explored the relationship between fluid balance,
intradialytic hypotension and outcomes in critically ill patients with acute kidney injury (AKI) …

Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 …

JA Silversides, R McMullan, LM Emerson… - Intensive Care …, 2022 - Springer
Purpose Fluid overload is common in critical illness and is associated with mortality. This
study investigated the feasibility of a randomised trial comparing conservative fluid …

[HTML][HTML] Liberal versus restrictive fluid therapy in critically ill patients

JA Silversides, A Perner, MLNG Malbrain - Intensive Care Medicine, 2019 - Springer
Administration of intravenous fluid is one of the most commonly applied therapies in critical
care, and has evolved from the replacement of water and electrolytes lost in diarrhoeal …

Repair of acute respiratory distress syndrome in COVID-19 by stromal cells (REALIST-COVID Trial): a multicenter, randomized, controlled clinical trial

EA Gorman, J Rynne, HJ Gardiner… - American journal of …, 2023 - atsjournals.org
Rationale: Mesenchymal stromal cells (MSCs) may modulate inflammation, promoting repair
in coronavirus disease (COVID-19)–related acute respiratory distress syndrome (ARDS) …

[HTML][HTML] Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: a phase 1 trial

E Gorman, M Shankar-Hari, P Hopkins… - …, 2021 - thelancet.com
Abstract Background Mesenchymal stromal cells (MSCs) may be of benefit in acute
respiratory distress syndrome (ARDS) due to immunomodulatory, reparative, and …