Cachexia is associated with decreased survival in cancer patients and has a prevalence of
up to 80%. The etiology of cachexia is poorly understood, and limited treatment options …

Abstract Thyroid transcription factor-1 (TTF-1) is a sensitive marker for pulmonary and
thyroid adenocarcinomas. The aim of this work was to determine its usefulness in distinction …

On the basis of clinical trials using first-generation epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitors (TKIs), it became a doctrine that V-Ki-ras2 Kirsten rat sarcoma viral …

The aim of our retrospective study was to analyze patterns of subtype specific metastatic
spread and to identify the time course of distant metastases. A consecutive series of 490 …

The tissue distribution and prognostic relevance of subtype‐specific proteins (ASCL1,
NEUROD1, POU2F3, YAP1) present an evolving area of research in small‐cell lung cancer …

Current guidelines lack comprehensive information on the metastatic site-specific role of
KRAS mutation in lung adenocarcinoma (LADC). We investigated the effect of KRAS …

An aim of molecular biomarkers is to stratify patients with cancer into disease subtypes
predictive of outcome, improving diagnostic precision beyond clinical descriptors such as …

Small cell lung cancer (SCLC) has recently been subcategorized into neuroendocrine (NE)‐
high and NE‐low subtypes showing 'immune desert'and 'immune oasis' phenotypes …

Background Platinum-based chemotherapy is the most common treatment in advanced-
stage lung adenocarcinoma. Because the clinical significance of KRAS mutational status in …

Introduction Although classic sensitizing mutations of epidermal growth factor receptor
(EGFR) are positive predictive markers for EGFR tyrosine kinase inhibitors (TKIs) in lung …