Colonization by Pneumocystis jirovecii and its role in disease

A Morris, KA Norris - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Although the incidence of Pneumocystis pneumonia (PCP) has decreased since the
introduction of combination antiretroviral therapy, it remains an important cause of disease in …

Pneumocystis: A Novel Pathogen in Chronic Obstructive Pulmonary Disease?

A Morris, FC Sciurba, KA Norris - COPD: Journal of Chronic …, 2008 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) results in significant morbidity and mortality.
Smoking has long been recognized as the primary risk factor for development of COPD, but …

[HTML][HTML] Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

T Bertero, WM Oldham, KA Cottrill… - The Journal of …, 2016 - Am Soc Clin Investig
Dysregulation of vascular stiffness and cellular metabolism occurs early in pulmonary
hypertension (PH). However, the mechanisms by which biophysical properties of the …

Association of Chronic Obstructive Pulmonary Disease Severity and Pneumocystis Colonization

A Morris, FC Sciurba, IP Lebedeva… - American journal of …, 2004 - atsjournals.org
Factors modulating the variable progression of chronic obstructive pulmonary disease
(COPD) are largely unknown, but infectious agents may play a role. Because Pneumocystis …

Prevalence and healthcare burden of fungal infections in the United States, 2018

E Rayens, KA Norris - Open forum infectious diseases, 2022 - academic.oup.com
Background Fungal infections are responsible for> 1.5 million deaths globally per year,
primarily in those with compromised immune function. This is concerning as the number of …

[HTML][HTML] Demographic and socioeconomic factors associated with fungal infection risk, United States, 2019

E Rayens, MK Rayens, KA Norris - Emerging Infectious Diseases, 2022 - ncbi.nlm.nih.gov
Fungal infections cause substantial rates of illness and death. Interest in the association
between demographic factors and fungal infections is increasing. We analyzed 2019 US …

Prevalence and clinical predictors of Pneumocystis colonization among HIV-infected men

A Morris, LA Kingsley, G Groner, IP Lebedeva… - Aids, 2004 - journals.lww.com
Background: The epidemiology and transmission of Pneumocystis are poorly understood.
The incidence of colonization, or detection of organisms without signs of disease, has been …

Airway Obstruction Is Increased in Pneumocystis-Colonized Human Immunodeficiency Virus-Infected Outpatients

A Morris, T Alexander, S Radhi, L Lucht… - Journal of clinical …, 2009 - Am Soc Microbiol
We investigated the relationship of Pneumocystis colonization, matrix metalloprotease levels
in sputum, and airway obstruction in a cohort of human immunodeficiency virus (HIV) …

CCR5 as a treatment target in pulmonary arterial hypertension

V Amsellem, L Lipskaia, S Abid, L Poupel… - Circulation, 2014 - Am Heart Assoc
Background—Pulmonary arterial hypertension (PH), whether idiopathic or related to
underlying diseases such as HIV infection, results from complex vessel remodeling involving …

Persistent Pneumocystis Colonization Leads to the Development of Chronic Obstructive Pulmonary Disease in a Nonhuman Primate Model of AIDS

TW Shipley, HM Kling, A Morris, S Patil… - The Journal of …, 2010 - academic.oup.com
Human immunodeficiency virus (HIV)–infected patients are at increased risk for
development of pulmonary complications, including chronic obstructive pulmonary disease …