Although the geographical context of ecological observations shapes ecological theory, the
global distribution of ecological studies has never been analyzed. Here, we document the …

Rationale and objective Auditory sensory gating, a biological measurement of the ability to
suppress the evoked response to the second of two auditory stimuli, is diminished in people …

Like many species, the model plant Arabidopsis thaliana exhibits multiple different life
histories in natural environments. We grew mutants impaired in different signaling pathways …

Mice deficient in BACE1 (beta-site APP cleaving enzyme 1) are healthy, fertile and appear
normal in gross anatomy, tissue histology, hematology and clinical chemistry. BACE1 …

We have generated RANK (receptor activator of NF-κB) nullizygous mice to determine the
molecular genetic interactions between osteoprotegerin, osteoprotegerin ligand, and RANK …

Background Some copy-number variants are associated with genomic disorders with
extreme phenotypic heterogeneity. The cause of this variation is unknown, which presents …

Context The α7 nicotinic acetylcholine receptor gene, CHRNA7, is associated with genetic
transmission of schizophrenia and related cognitive and neurophysiological sensory gating …

Background The ability of T cells, acting independently of antibodies, to control malaria
parasite growth in people has not been defined. If such cell-mediated immunity was shown …

Objective: Nicotinic acetylcholine receptors are possible therapeutic targets for
schizophrenia, as shown by neurobiological and molecular evidence for deficiencies in …

Context Limbic structures are implicated in the genesis of attention-deficit/hyperactivity
disorder (ADHD) by the presence of mood and cognitive disturbances in affected individuals …