Avian influenza virus (H5N1): a threat to human health

JSM Peiris, MD De Jong, Y Guan - Clinical microbiology reviews, 2007 - Am Soc Microbiol
Pandemic influenza virus has its origins in avian influenza viruses. The highly pathogenic
avian influenza virus subtype H5N1 is already panzootic in poultry, with attendant economic …

Human infection with highly pathogenic H5N1 influenza virus

A Gambotto, SM Barratt-Boyes, MD de Jong… - The Lancet, 2008 - thelancet.com
Highly pathogenic H5N1 influenza A viruses have spread relentlessly across the globe
since 2003, and they are associated with widespread death in poultry, substantial economic …

Avian influenza A (H5N1)

MD de Jong, TT Hien - Journal of clinical virology, 2006 - Elsevier
Since their reemergence in 2003, highly pathogenic avian influenza A (H5N1) viruses have
reached endemic levels among poultry in several southeast Asian countries and have …

[HTML][HTML] Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

MD De Jong, CP Simmons, TT Thanh, VM Hien… - Nature medicine, 2006 - nature.com
Abstract Avian influenza A (H5N1) viruses cause severe disease in humans,, but the basis
for their virulence remains unclear. In vitro and animal studies indicate that high and …

[HTML][HTML] Oseltamivir resistance during treatment of influenza A (H5N1) infection

MD De Jong, TT Thanh, TH Khanh… - New england journal …, 2005 - Mass Medical Soc
Influenza A (H5N1) virus with an amino acid substitution in neuraminidase conferring high-
level resistance to oseltamivir was isolated from two of eight Vietnamese patients during …

[HTML][HTML] Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma

MD de Jong, BV Cam, PT Qui, VM Hien… - … England Journal of …, 2005 - Mass Medical Soc
In southern Vietnam, a four-year-old boy presented with severe diarrhea, followed by
seizures, coma, and death. The cerebrospinal fluid contained 1 white cell per cubic …

[HTML][HTML] Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study

B Schurink, E Roos, T Radonic, E Barbe… - The Lancet …, 2020 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets
multiple organs and causes severe coagulopathy. Histopathological organ changes might …

[HTML][HTML] Baloxavir marboxil for uncomplicated influenza in adults and adolescents

FG Hayden, N Sugaya, N Hirotsu, N Lee… - … England Journal of …, 2018 - Mass Medical Soc
Background Baloxavir marboxil is a selective inhibitor of influenza cap-dependent
endonuclease. It has shown therapeutic activity in preclinical models of influenza A and B …

Dissemination of the mcr-1 colistin resistance gene

MS Arcilla, JM van Hattem, S Matamoros… - The Lancet infectious …, 2016 - thelancet.com
1 Liu YY, Wang Y, Walsh TR, et al. Emergence of plasmid-mediated colistin resistance
mechanism MCR-1 in animals and human beings in China: a microbiological and molecular …

Import and spread of extended-spectrum β-lactamase-producing Enterobacteriaceae by international travellers (COMBAT study): a prospective, multicentre cohort …

MS Arcilla, JM van Hattem, MR Haverkate… - The Lancet infectious …, 2017 - thelancet.com
Background International travel contributes to the dissemination of antimicrobial resistance.
We investigated the acquisition of extended-spectrum β-lactamase-producing …