Recent advances in the detection of brown adipose tissue in adult humans: a review

FJ Ong, BA Ahmed, SM Oreskovich, DP Blondin… - Clinical …, 2018 - portlandpress.com
The activation of brown adipose tissue (BAT) is associated with reductions in circulating
lipids and glucose in rodents and contributes to energy expenditure in humans indicating …

[PDF][PDF] Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota

BA Ahmed, FJ Ong, NG Barra, DP Blondin, E Gunn… - Cell Reports …, 2021 - cell.com
In rodents, lower brown adipose tissue (BAT) activity is associated with greater liver
steatosis and changes in the gut microbiome. However, little is known about these …

Multiple‐mouse MRI

NA Bock, NB Konyer… - Magnetic Resonance in …, 2003 - Wiley Online Library
Several theoretical parallel‐imaging approaches are evaluated that seek to improve the
efficiency of an MRI experiment involving multiple small samples, such as mice. The best …

129Xe MRI ventilation defects in ever-hospitalised and never-hospitalised people with post-acute COVID-19 syndrome

HK Kooner, MJ McIntosh… - BMJ open …, 2022 - bmjopenrespres.bmj.com
Background Patients often report persistent symptoms beyond the acute infectious phase of
COVID-19. Hyperpolarised 129Xe MRI provides a way to directly measure airway functional …

Optimizing T1-weighted imaging of cortical myelin content at 3.0 T

NA Bock, E Hashim, R Janik, NB Konyer, M Weiss… - Neuroimage, 2013 - Elsevier
With increases in the sensitivity and resolution of anatomical MRI for the brain, methods for
mapping the organization of the cerebral cortex by imaging its myelin content have …

MRI reveals human brown adipose tissue is rapidly activated in response to cold

SM Oreskovich, FJ Ong, BA Ahmed… - Journal of the …, 2019 - academic.oup.com
Context In rodents, cold exposure induces the activation of brown adipose tissue (BAT) and
the induction of intracellular triacylglycerol (TAG) lipolysis. However, in humans, the kinetics …

Specific Ventilation in Severe Asthma Evaluated with Noncontrast Tidal Breathing 1H MRI

DPI Capaldi, NB Konyer, M Kjarsgaard… - Radiology …, 2023 - pubs.rsna.org
Purpose To determine if proton (1H) MRI–derived specific ventilation is responsive to
bronchodilator (BD) therapy and associated with clinical biomarkers of type 2 airway …

Reproducibility of hyperpolarized 129Xe MRI ventilation defect percent in severe asthma to evaluate clinical trial feasibility

S Svenningsen, M McIntosh, A Ouriadov… - Academic …, 2021 - Elsevier
Rationale and Objectives 129 Xe MRI has been developed to noninvasively visualize and
quantify the functional consequence of airway obstruction in asthma. Its widespread …

Impaired cold-stimulated supraclavicular Brown adipose tissue activity in young boys with obesity

BA Ahmed, N Varah, FJ Ong, DP Blondin, E Gunn… - Diabetes, 2022 - Am Diabetes Assoc
Childhood obesity is a growing worldwide problem. In adults, lower cold-induced brown
adipose tissue (BAT) activity is linked to obesity and metabolic dysfunction; this relationship …

Comparison of MR imaging breast coils

NB Konyer, EA Ramsay, MJ Bronskill, DB Plewes - Radiology, 2002 - pubs.rsna.org
In one volunteer, five breast coils were evaluated for signal-to-noise ratio (SNR), uniformity,
comfort, subject orientation, access to the breast, and unilateral imaging options. The four …