Idiopathic pulmonary fibrosis: new insights to functional characteristics at diagnosis

A Cortes-Telles, L Forkert, DE O'Donnell… - Canadian respiratory …, 2014 - hindawi.com
BACKGROUND: The lung function of patients with idiopathic pulmonary fibrosis (IPF) has
not been characterized in detail. OBJECTIVE: To characterize the heterogeneous …

High oxygen delivery to preserve exercise capacity in patients with idiopathic pulmonary fibrosis treated with nintedanib. Methodology of the HOPE-IPF study

CJ Ryerson, PG Camp, ND Eves… - Annals of the …, 2016 - atsjournals.org
Rationale: Pulmonary rehabilitation improves dyspnea and exercise capacity in idiopathic
pulmonary fibrosis (IPF); however, it is unknown whether breathing high amounts of oxygen …

Systemic Determinants of Exercise Intolerance in Patients With Fibrotic Interstitial Lung Disease and Severely Impaired DLCO

RM Smyth, MD James, SG Vincent, KM Milne… - Respiratory …, 2023 - rc.rcjournal.com
BACKGROUND: The precise mechanisms driving poor exercise tolerance in patients with
fibrotic interstitial lung diseases (fibrotic ILDs) showing a severe impairment in single-breath …

Physiological underpinnings of exertional dyspnoea in mild fibrosing interstitial lung disease

RM Smyth, JA Neder, MD James, SG Vincent… - Respiratory Physiology …, 2023 - Elsevier
The functional disturbances driving “out-of-proportion” dyspnoea in patients with fibrosing
interstitial lung disease (f-ILD) showing only mild restrictive abnormalities remain poorly …

Oxygen supplementation during exercise improves leg muscle fatigue in chronic fibrotic interstitial lung disease

M Marillier, AC Bernard, S Verges, O Moran-Mendoza… - Thorax, 2021 - thorax.bmj.com
Background Exercise-induced hypoxaemia is a hallmark of chronic fibrotic interstitial lung
disease (f-ILD). It remains unclear whether patients' severe hypoxaemia may exaggerate …

Fine crackles on chest auscultation in the early diagnosis of idiopathic pulmonary fibrosis: a prospective cohort study

O Moran-Mendoza, T Ritchie… - BMJ open respiratory …, 2021 - bmjopenrespres.bmj.com
Introduction Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease (ILD) with a
poor prognosis. Early diagnosis and treatment of IPF may increase lifespan and preserve …

Chronic breathlessness in patients with idiopathic pulmonary fibrosis: a major challenge for caregivers

DE O'Donnell, JA Neder, I Harle… - Expert review of …, 2016 - Taylor & Francis
Introduction: Idiopathic pulmonary fibrosis (IPF) is one of the most common forms of
interstitial lung disease, with a median survival time of two to five years. Most patients with …

Influence of exertional hypoxemia on cerebral oxygenation in fibrotic interstitial lung disease

M Marillier, AC Bernard, S Verges… - Respiratory Physiology …, 2021 - Elsevier
It is unknown whether hypoxemia, a hallmark of fibrotic interstitial lung disease (f-ILD), may
impair cerebral oxygenation during exercise in these patients. Twenty-seven patients [23 …

A comprehensive and practical approach to the management of idiopathic pulmonary fibrosis

O Moran-Mendoza, R Colman, M Kalluri… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Idiopathic pulmonary fibrosis (IPF) is a debilitating, progressive, and fatal
fibrotic pulmonary disease with a prognosis comparable to that of lung cancer. IPF …

Cost‐Effectiveness of LTBI Treatment for TB Contacts in British Columbia

MC Tan, CA Marra, M Sadatsafavi, F Marra… - Value in …, 2008 - Wiley Online Library
Background: Contacts of patients with active tuberculosis (“TB contacts”) with a tuberculin
skin test (TST) size≥ 5 mm are currently recommended treatment for latent TB infection …