Purpose Polygenic risk influences susceptibility to cancer. We assessed whether polygenic
risk scores could be used in conjunction with other predictors of future disease status in cost …

Background Many countries are exploring the potential of telehealth interventions to
manage the rising number of people with chronic disorders. However, evidence of the …

This paper reviews the literature on the economics of intellectual property rights. Intellectual
property rights (IPR) refer to the legal protection accorded to certain inventions or creations …

Objective To assess whether non-clinical staff can effectively manage people at high risk of
cardiovascular disease using digital health technologies. Design Pragmatic, multicentre …

Background The prevalence of obesity has increased in the United Kingdom, and reliably
measuring the impact on quality of life and the total healthcare cost from obesity is key to …

Abstract Background The Cancer Drugs Fund (CDF) will have spent more than£ 1 billion
between October 2010 and the introduction of reforms to its structure and operations in July …

Estimates of the marginal effect of measures of adiposity such as body mass index (BMI) on
healthcare costs are important for the formulation and evaluation of policies targeting …

Background We aimed to estimate the causal effect of health conditions and risk factors on
social and socioeconomic outcomes in UK Biobank. Evidence on socioeconomic impacts is …

Understanding the causal impact that clinical risk factors have on healthcare-related costs is
critical to evaluate healthcare interventions. Here, we used a genetically-informed design …

Objective To investigate recruitment and retention, data collection methods and the
acceptability of a 'within-consultation'complex intervention designed to reduce antibiotic …