User profiles for "author:Shabir A Madhi"

Shabir A. Madhi

University of the Witwatersrand
Verified email at wits.ac.za
Cited by 60120

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

H Nair, DJ Nokes, BD Gessner, M Dherani, SA Madhi… - The Lancet, 2010 - thelancet.com
Background The global burden of disease attributable to respiratory syncytial virus (RSV)
remains unknown. We aimed to estimate the global incidence of and mortality from episodes …

[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a …

T Shi, DA McAllister, KL O'Brien, EAF Simoes… - The Lancet, 2017 - thelancet.com
Background We have previously estimated that respiratory syncytial virus (RSV) was
associated with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) …

Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis

H Nair, WA Brooks, M Katz, A Roca, JA Berkley… - The Lancet, 2011 - thelancet.com
Background The global burden of disease attributable to seasonal influenza virus in children
is unknown. We aimed to estimate the global incidence of and mortality from lower …

[HTML][HTML] Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South …

M Voysey, SAC Clemens, SA Madhi, LY Weckx… - The Lancet, 2021 - thelancet.com
Background A safe and efficacious vaccine against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control …

[PDF][PDF] SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses

W Dejnirattisai, J Huo, D Zhou, J Zahradník, P Supasa… - Cell, 2022 - cell.com
On 24 th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B. 1.1.
529 was announced, containing far more mutations in Spike (S) than previously reported …

[HTML][HTML] Efficacy of the ChAdOx1 nCoV-19 Covid-19 vaccine against the B. 1.351 variant

SA Madhi, V Baillie, CL Cutland… - … England Journal of …, 2021 - Mass Medical Soc
Background Assessment of the safety and efficacy of vaccines against the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) in different populations is essential, as is …

[HTML][HTML] Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a …

M Voysey, SAC Clemens, SA Madhi, LY Weckx… - The Lancet, 2021 - thelancet.com
Summary Background The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for
emergency use by the UK regulatory authority, Medicines and Healthcare products …

[HTML][HTML] Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants

B Kampmann, SA Madhi, I Munjal… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether vaccination during pregnancy could reduce the burden of respiratory
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …

[HTML][HTML] Nirsevimab for prevention of RSV in healthy late-preterm and term infants

LL Hammitt, R Dagan, Y Yuan… - … England Journal of …, 2022 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract
infection and hospitalization in infants. Nirsevimab is a monoclonal antibody to the RSV …

[HTML][HTML] Early antiretroviral therapy and mortality among HIV-infected infants

A Violari, MF Cotton, DM Gibb… - … England Journal of …, 2008 - Mass Medical Soc
Background In countries with a high seroprevalence of human immunodeficiency virus type
1 (HIV-1), HIV infection contributes significantly to infant mortality. We investigated …