The aim of the present study was to examine the efficacy of tumor-targeting Salmonella
typhimurium A1-R treatment following anti-vascular endothelial growth factor (VEGF) …

Background: Fluorescence-guided surgery (FGS) can enable successful cancer surgery
where bright-light surgery often cannot. There are three important issues for FGS going …

Squamous cell carcinoma of the cervix, highly prevalent in the developing world, is often
metastatic and treatment resistant with no standard treatment protocol. Our laboratory …

Simple Summary Chemotherapy of solid tumors has made very slow progress over many
decades. A major problem has been that solid tumors very often contain non-dividing cells …

Quiescent cancer cells are resistant to cytotoxic agents which target only proliferating cancer
cells. Time-lapse imaging demonstrated that tumor-targeting Salmonella typhimurium A1-R …

The aim of this study is to determine the efficacy of tumor‐targeting Salmonella typhimurium
A1‐R (A1‐R) on pancreatic cancer patient‐derived orthotopic xenografts (PDOX). The …

A major impediment to the response of tumors to chemotherapy is that the large majority of
cancer cells within a tumor are quiescent in G 0/G 1, where cancer cells are resistant to …

Invasive cancer cells are a critical target in order to prevent metastasis. In the present report,
we demonstrate real-time visualization of cell cycle kinetics of invading cancer cells in 3 …

Adenovirus serotype 5 (Ad5) is widely and frequently used as a virus vector in cancer gene
therapy and oncolytic virotherapy. Oncolytic virotherapy is a novel antitumor treatment for …

A patient-derived nude-mouse model of soft-tissue sarcoma has been established and
treated in the following groups:(1) untreated controls;(2) gemcitabine (GEM)(80 mg/kg, ip …