[HTML][HTML] FinnGen provides genetic insights from a well-phenotyped isolated population

MI Kurki, J Karjalainen, P Palta, TP Sipilä… - Nature, 2023 - nature.com
Population isolates such as those in Finland benefit genetic research because deleterious
alleles are often concentrated on a small number of low-frequency variants (0.1%≤ minor …

FinnGen: Unique genetic insights from combining isolated population and national health register data

MI Kurki, J Karjalainen, P Palta, TP Sipilä… - MedRxiv, 2022 - medrxiv.org
Population isolates such as Finland provide benefits in genetic studies because the allelic
spectrum of damaging alleles in any gene is often concentrated on a small number of low …

Sleep apnoea is a risk factor for severe COVID-19

S Strausz, T Kiiskinen, M Broberg… - BMJ Open …, 2021 - bmjopenrespres.bmj.com
Background Obstructive sleep apnoea (OSA) is associated with higher body mass index
(BMI), diabetes, older age and male gender, which are all risk factors for severe COVID-19 …

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health

S Strausz, S Ruotsalainen, HM Ollila… - European …, 2021 - Eur Respiratory Soc
There is currently limited understanding of the genetic aetiology of obstructive sleep apnoea
(OSA). We aimed to identify genetic loci associated with OSA risk, and to test if OSA and its …

Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland

S Strausz, AS Havulinna, T Tuomi, A Bachour… - BMJ open, 2018 - bmjopen.bmj.com
Objective To evaluate if obstructive sleep apnoea (OSA) modifies the risk of coronary heart
disease, type 2 diabetes (T2D) and diabetic complications in a gender-specific fashion …

[HTML][HTML] Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population

MI Kurki, J Karjalainen, P Palta, TP Sipilä… - Nature, 2023 - nature.com
In the version of this article initially published, author Marianna Niemi, now affiliated with the
TAUCHI Research Center and the Faculty of Medicine and Health Technology in Tampere …

The relation of severe malocclusion to patients' mental and behavioral disorders, growth, and speech problems

A Koskela, A Neittaanmäki, K Rönnberg… - European Journal of …, 2021 - academic.oup.com
Background Severe malocclusions appear in up to 20 per cent of the population. Many
neuropsychiatric diseases are likely to have a neurodevelopmental, partially genetic …

[HTML][HTML] Peri-and postoperative complications in Le Fort I osteotomies

KVM Kotaniemi, J Suojanen, T Palotie - Journal of Cranio-Maxillofacial …, 2021 - Elsevier
This retrospective study was performed to report the peri-and postoperative complications
encountered by patients who underwent Le Fort I osteotomy, as well as predictor variables …

Comparison of postoperative skeletal stability of maxillary segments after Le Fort I osteotomy, using patient-specific implant versus mini-plate fixation

KVM Kotaniemi, A Heliövaara, M Kotaniemi… - Journal of Cranio …, 2019 - Elsevier
Abstract Background Three-dimensionally (3D) designed osteotomies and customised
osteosynthesis are rapidly becoming standard in maxillofacial reconstructive and deformity …

Oral appliance in sleep apnea treatment: respiratory and clinical effects and long-term adherence

P Bachour, A Bachour, P Kauppi, P Maasilta… - Sleep and …, 2016 - Springer
Purpose There is an increasing tendency to use oral appliance (OA) as an alternative
treatment for sleep apnea. Here we report the long-term adherence and clinical effects of OA …