International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study
Background Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity
and mortality worldwide, and accurate estimates of the prevalence of this disease are …
and mortality worldwide, and accurate estimates of the prevalence of this disease are …
Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial
…, R Pauwels, J Vestbo, P Jones, N Pride, A Gulsvik… - The Lancet, 2003 - thelancet.com
Background Inhaled longacting β 2 agonists improve lung function and health status in
symptomatic chronic obstructive pulmonary disease (COPD), whereas inhaled corticosteroids …
symptomatic chronic obstructive pulmonary disease (COPD), whereas inhaled corticosteroids …
[HTML][HTML] A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci
There is considerable variability in the susceptibility of smokers to develop chronic obstructive
pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α 1 -…
pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α 1 -…
Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Smoking is a leading global cause of disease and mortality 1 . We established the Oxford-GlaxoSmithKline
study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association …
study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association …
Variants in FAM13A are associated with chronic obstructive pulmonary disease
…, R Tal-Singer, DA Lomas, P Bakke, A Gulsvik… - Nature …, 2010 - nature.com
We performed a genome-wide association study for chronic obstructive pulmonary disease (COPD)
in three population cohorts, including 2,940 cases and 1,380 controls who were …
in three population cohorts, including 2,940 cases and 1,380 controls who were …
Gender differences in COPD: are women more susceptible to smoking effects than men?
IC Sørheim, A Johannessen, A Gulsvik, PS Bakke… - Thorax, 2010 - thorax.bmj.com
Background The number of female smokers developing chronic obstructive pulmonary disease
(COPD) is rapidly increasing, but whether or not there exists a differential susceptibility …
(COPD) is rapidly increasing, but whether or not there exists a differential susceptibility …
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis
…, DA Lomas, P Bakke, A Gulsvik… - The lancet Respiratory …, 2014 - thelancet.com
Background The genetic risk factors for susceptibility to chronic obstructive pulmonary disease
(COPD) are still largely unknown. Additional genetic variants are likely to be identified by …
(COPD) are still largely unknown. Additional genetic variants are likely to be identified by …
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
…, RG Barr, D Sparrow, AA Litonjua, P Bakke, A Gulsvik… - Nature …, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide 1 .
We performed a genetic association study in 15,256 cases and 47,936 controls, with …
We performed a genetic association study in 15,256 cases and 47,936 controls, with …
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
…, F Dudbridge, R Ewert, C Gieger, A Gulsvik… - Nature …, 2019 - nature.com
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …
Comparison of spirometry criteria for the diagnosis of COPD: results from the BOLD study
…, P Burney, PL Enright, A Gulsvik… - European …, 2009 - Eur Respiratory Soc
Published guidelines recommend spirometry to accurately diagnose chronic obstructive
pulmonary disease (COPD). However, even spirometry-based COPD prevalence estimates can …
pulmonary disease (COPD). However, even spirometry-based COPD prevalence estimates can …