Hypersensitivity pneumonitis: radiologic phenotypes are associated with distinct survival time and pulmonary function trajectory

…, KE Konopka, EA Belloli, JS Sheth, ES White, C Holtze… - Chest, 2019 - Elsevier
Background Hypersensitivity pneumonitis (HP) is an interstitial lung disease with a better
prognosis, on average, than idiopathic pulmonary fibrosis (IPF). We compare survival time and …

The cost of ICU delirium and coma in the intensive care unit patient

EE Vasilevskis, R Chandrasekhar, CH Holtze… - Medical care, 2018 - journals.lww.com
Objectives: To specify the association between the daily occurrence of delirium in the ICU
with costs of ICU care accounting for time-varying illness severity and death. Research Design…

Healthcare utilisation and costs in the diagnosis and treatment of progressive-fibrosing interstitial lung diseases

C Holtze, K Flaherty, M Kreuter, F Luppi… - European …, 2018 - Eur Respiratory Soc
There are over 200 interstitial lung diseases (ILDs). In addition to patients with idiopathic
pulmonary fibrosis (IPF), a percentage of patients with other ILDs also develop progressive …

Development and validation of a radiological diagnosis model for hypersensitivity pneumonitis

…, JS Sheth, ES White, C Holtze… - European …, 2018 - Eur Respiratory Soc
High-resolution computed tomography (HRCT) may be useful for diagnosing hypersensitivity
pneumonitis. Here, we develop and validate a radiological diagnosis model and model-…

[HTML][HTML] Patient and site characteristics associated with pirfenidone and nintedanib use in the United States; an analysis of idiopathic pulmonary fibrosis patients …

CH Holtze, EA Freiheit, SL Limb, JL Stauffer… - Respiratory …, 2020 - Springer
Background Pragmatic use of the anti-fibrotic medications pirfenidone and nintedanib for
idiopathic pulmonary fibrosis (IPF) in the United States (US) has not been studied and may be …

[HTML][HTML] Frailty and geriatric conditions in older patients with idiopathic pulmonary fibrosis

…, EA Belloli, ML Salisbury, ES White, CH Holtze… - Respiratory …, 2019 - Elsevier
Background Functional status, an important predictor of health outcomes in older patients,
has not been studied in an IPF population. This study aimed to determine the prevalence of …

A new paradigm of interactive artery/vein separation in noncontrast pulmonary CT imaging using multiscale topomorphologic opening

Z Gao, RW Grout, C Holtze… - IEEE Transactions on …, 2012 - ieeexplore.ieee.org
Distinguishing pulmonary arterial and venous (A/V) trees via in vivo imaging is a critical first
step in the quantification of vascular geometry for the purpose of diagnosing several …

Time to diagnosis of idiopathic pulmonary fibrosis in the IPF-PRO Registry

LD Snyder, C Mosher, CH Holtze… - BMJ Open …, 2020 - bmjopenrespres.bmj.com
Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease with high mortality.
Patient characteristics associated with diagnostic delays are not well described. Methods …

Multi-scale topo-morphometric opening of arteries and veins: an evaluative study via pulmonary CT imaging

Z Gao, C Holtze, R Grout, M Sonka, E Hoffman… - Advances in Visual …, 2010 - Springer
Distinguishing pulmonary arterial and venous (A/V) trees via in vivo imaging is essential for
quantification of vascular geometry useful to diagnose several pulmonary diseases. A multi-…

Utility Of High Resolution Computed Tomography For Diagnosis Of Hypersensitivity Pneumonia

…, E Belloli, JS Sheth, ES White, CH Holtze… - A43. NON-IPF ILD …, 2017 - atsjournals.org
METHODS: ILD patients were identified via HP ICD-9 code search and review of multidisciplinary
ILD conference minutes. Eligible patients had a thin-section, inspiratory HRCT, with …