… of Education of Japan to JA, HH, JK, KS, KN, and K. Kuwano, and Health and Labour
Sciences Research Grants from the Ministry of Health Labour and Welfare of Japan to JA and K. …

Increasing attention is being paid to the role of extracellular vesicles (EVs) in various lung
diseases. EVs are released by a variety of cells, including respiratory cells and immune cells, …

It is currently thought that extracellular vesicles (EVs), such as exosomes and microvesicles,
play an important autocrine/paracrine role in intercellular communication. EVs package …

Using a computational model, we investigated the effect of the morphologically determined
increased airway smooth muscle mass, adventitial mass, and submucosal mass observed in …

The purpose of this study was to compare the dimensions of the peripheral airways in fatal
asthma with those from patients with nonfatal asthma, mild COPD, and normal lung function. …

… i–k BEAS-2B were transfected with control siRNA or NCOA4 siRNA 48 h before control or
CSE treatment. i BODIPY staining (n = 5 independent experiments), j LDH assay (n = 4 …

… The nuclei of tissue sections were stripped of proteins by incubation with 20 ug/rnl of proteinase
K for 10 min and immediately fixed in 4010 paraformaldehyde at room temperature (RT) …

… Kuwano conception and design of research; JA, JK, NT, SI, SF, H. Hara, HY, … Hano, KN,
and K. Kuwano approved final version of manuscript; JA edited and revised manuscript. …

Reepithelialization of remodeled air spaces with bronchial epithelial cells is a prominent
pathological finding in idiopathic pulmonary fibrosis (IPF) and is implicated in IPF pathogenesis. …

Antimicrobial peptides contribute to innate host defense against a number of bacteria and
fungal pathogens. Some of antimicrobial synthetic peptides were systemically administered in …