[HTML][HTML] Vorasidenib in IDH1-or IDH2-mutant low-grade glioma

…, J Mendez, S Yust-Katz, L Welsh… - … England Journal of …, 2023 - Mass Medical Soc
Background Isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas are malignant brain
tumors that cause considerable disability and premature death. Vorasidenib, an oral brain-…

[HTML][HTML] Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

…, D Cunningham, I Chau, N Starling, N Turner, L Welsh… - Nature cancer, 2021 - nature.com
Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune monitoring
(CAPTURE) ( NCT03226886 ) is a prospective cohort study of COVID-19 immunity in …

Spirometry centile charts for young Caucasian children: the Asthma UK Collaborative Initiative

…, M Silverman, GL Hall, L Welsh… - American journal of …, 2009 - search.proquest.com
Advances in spirometry measurement techniques have made it possible to obtain
measurements in children as young as 3 years of age; however, in practice, application remains …

The EPICure study: maximal exercise and physical activity in school children born extremely preterm

L Welsh, J Kirkby, S Lum, D Odendaal, N Marlow… - Thorax, 2010 - thorax.bmj.com
Rationale Evidence regarding exercise capacity and physical activity in children born
extremely preterm (EP) is limited. Since survivors remain at high risk for developing …

Effects of physical conditioning on children and adolescents with asthma

L Welsh, JG Kemp, RGD Roberts - Sports medicine, 2005 - Springer
More than 40 years ago, the effects of exertional dyspnoea and the associated fear of an
asthma attack usually lead to an avoidance of physical activity amongst asthmatic children. This …

Nature and severity of lung function abnormalities in extremely pre-term children at 11 years of age

S Lum, J Kirkby, L Welsh, N Marlow… - European …, 2011 - Eur Respiratory Soc
Advances in neonatal care have resulted in increased survival of children born extremely
pre-term (EP). Nevertheless the incidence of bronchopulmonary dysplasia and long-term …

[HTML][HTML] Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study

…, D Cunningham, I Chau, N Starling, N Turner, L Welsh… - Nature Cancer, 2021 - nature.com
Patients with cancer have higher COVID-19 morbidity and mortality. Here we present the
prospective CAPTURE study, integrating longitudinal immune profiling with clinical annotation. …

Role of capsid structure and membrane protein processing in determining the size and copy number of peptides displayed on the major coat protein of filamentous …

…, SA Petukhov, MF Symmons, LC Welsh… - Journal of molecular …, 1996 - Elsevier
Filamentous bacteriophage virions can be engineered to display small foreign peptides in
the N-terminal regions of all 2700 copies of the major coat protein (pVIII), but larger peptides …

[HTML][HTML] Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood

…, DJ Amor, LW Doyle, S Ranganathan, L Welsh… - Nature …, 2019 - nature.com
More than 7 million individuals have been conceived by Assisted Reproductive Technologies
(ART) and there is clear evidence that ART is associated with a range of adverse early life …

Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study

…, WT Huang, KM Lai, S Yeh, D Palmer, L Welsh… - The Lancet …, 2023 - thelancet.com
Background FGFR alterations are reported across various malignancies and might act as
oncogenic drivers in multiple histologies. Erdafitinib is an oral, selective pan-FGFR tyrosine …