Cough is one of the most common presenting symptoms of COVID-19, along with fever and
loss of taste and smell. Cough can persist for weeks or months after SARS-CoV-2 infection, …

Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat
because many pulmonary and extrapulmonary conditions can present with chronic cough…

We have identified the tracheal and laryngeal afferent nerves regulating cough in anaesthetized
guinea‐pigs. Cough was evoked by electrical or mechanical stimulation of the tracheal …

Vagal sensory neurons constitute the major afferent supply to the airways and lungs. Subsets
of afferents are defined by their embryological origin, molecular profile, neurochemistry, …

Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated
sensory nerves play essential roles in regulating cough. These vagal sensory nerves …

Coughing is initiated by activation of mechanically and chemically sensitive vagal afferent
nerves innervating the airways. All afferent nerve subtypes innervating the airways can …

Chronic cough is a common symptom that can be a daunting challenge for clinicians since
treatment of the underlying cause does not always provide adequate relief, an obvious cause …

Reports from individual centres suggest a preponderance of females with chronic cough.
Females also have heightened cough reflex sensitivity. Here we have reviewed the age and …

Cough initiated from the trachea and larynx in anaesthetized guinea‐pigs is mediated by
capsaicin‐insensitive, mechanically sensitive vagal afferent neurones. Tachykinin‐containing, …

… Correspondence and requests for reprints should be addressed to Stuart B. Mazzone, Ph.D.,
The Howard Florey Institute, University of Melbourne, Parkville, Victoria, Australia 3010. E-…