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Evaluation of the Post-COVID-19 Functional Status (PCFS) Scale in a cohort of patients recovering from hypoxemic SARS-CoV-2 pneumonia
  1. Naïla Benkalfate1,
  2. Emmanuel Eschapasse1,
  3. Thomas Georges1,
  4. Camille Leblanc1,
  5. Stephanie Dirou1,
  6. Lise Melscoet1,
  7. Anne-Laure Chéné1,
  8. Delphine Horeau-Langlard1,
  9. Charlotte Bry1,
  10. Arnaud Chambellan2,
  11. Aymeric Nicolas3,
  12. Defrance Claire3,
  13. Renan Liberge3,
  14. Matilde Karakachoff4,
  15. Jean-Benoit Hardouin5,
  16. François-Xavier Blanc6 and
  17. Patricia Lemarchand6
  1. 1Nantes University, CHU Nantes, Departement of Respiratory Medicine, l'institut du thorax, F-44000 Nantes, Pays de la Loire, France
  2. 2Nantes University, CHU Nantes, Department of Physiology, l’Institut du thorax, Laboratoire MIP, F-44000 Nantes, France
  3. 3Nantes University, CHU Nantes, Department of Radiology, F-44000 Nantes, France
  4. 4Nantes University, CHU Nantes, INSERM, Clinique des données, CIC 1413, F-44000 Nantes, France
  5. 5Nantes Université, Univ Tours, CHU Nantes, INSERM, MethodS in Patients-centered outcomes and HEalth Research, SPHERE, F-44000 Nantes, France
  6. 6Nantes University, CHU Nantes, CNRS, INSERM, l’institut du thorax, F-44000 Nantes, France
  1. Correspondence to Dr Patricia Lemarchand; patricia.lemarchand{at}univ-nantes.fr

Abstract

Introduction COVID-19 sequelae are numerous and multisystemic, and how to evaluate those symptomatic patients is a timely issue. Klok et al proposed the Post-COVID-19 Functional Status (PCFS) Scale as an easy tool to evaluate limitations related to persistent symptoms. Our aim was to analyse PCFS Scale ability to detect functional limitations and its correlation with quality of life in a cohort of patients, 2–9 months after hospitalisation for COVID-19 hypoxemic pneumonia.

Methods PCFS Scale was evaluated in 121 patients together with quality of life and dyspnoea questionnaires, pulmonary function tests and CT scans.

Results We observed a high correlation with multiple questionnaires (Short Form-36, Hospital Anxiety and Depression Scale, modified Medical Research Council, end Borg Six-Minute Walk Test), making the PCFS Scale a quick and global tool to evaluate functional limitations related to various persistent symptoms following COVID-19 pneumonia.

Discussion The PCFS Scale seems to be a suitable instrument to screen for patients who will require careful follow-up after COVID-19 hypoxemic pneumonia even in the absence of pulmonary sequelae.

  • COVID-19
  • viral infection
  • respiratory infection
  • pneumonia

Data availability statement

Data are available upon reasonable request. The data are deidentified participant data, they are available from MK and data reuse will be allowed limited to academic research and to non-commercial use only, after evaluation of research project.

http://creativecommons.org/licenses/by-nc/4.0/

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Data availability statement

Data are available upon reasonable request. The data are deidentified participant data, they are available from MK and data reuse will be allowed limited to academic research and to non-commercial use only, after evaluation of research project.

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Footnotes

  • Contributors NB, EE and PL contributed to the study design, patient enrolment, data analysis and writing of the report. MK and J-BH contributed to the study design and data analysis. TG, CL, DH-L, LM, A-LC, SD, CB, AC and F-XB contributed to patient enrolment and follow-up. AN, DC and RL contributed to chest CT scan acquisition and analysis. PL was the author responsible for the overall content as the guarantor.

  • Funding This work was supported by the Institut de Recherche en Santé Respiratoire des Pays de la Loire. The authors thank the cluster LUNG innOvatiOn (LUNG O2) for logistic support.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.